Summary: For over a century, potassium ions were viewed as mere passengers in the brain—particles that flow through channels ...

Researchers from the National Institute for Physiological Sciences, Nagoya City University, and Tokyo Metropolitan Institute ...

In a phase 3 trial, the agent reduces seizure frequency by up to 53% in treatment-resistant focal epilepsy, with rapid onset ...

Potassium channels are essential membrane proteins that enable the selective and rapid transport of K⁺ ions, a process fundamental to cellular excitability and signal transduction. Recent research has ...

Potassium channels are openings that allow charged potassium atoms to cross the cell membrane. Voltage-gated potassium channels — which open only when a specific voltage is reached across the cell ...

Researchers have discovered a new mechanism for potassium channel inhibitor entry, which could improve the specificity of drugs targeting the channel. Upon binding to calcium ions, BK channels allow ...

Japanese researchers have uncovered how the functionality of KCNQ2/3 potassium channels is directly tied to their correct positioning in neurons, with implications for certain epilepsies. The study ...

(Up) Molecular structure of the selectivity filter of a KcsA potassium channel. Adjacent carbonyl rings exhibit a 27 degree rotation. Inspired by this structural feature, bi-layer graphene ...

Voltage-gated potassium (Kv) channels play an important role in modulating the electrical activity of cells, opening in response to changes in membrane voltage and allowing potassium ions to escape.

Underlying every thought, heartbeat and movement are ion channels, busily conducting high-speed streams of ions into cells, like subway trains coursing through tunnels. Ion channels span the cellular ...